The Foundation is supported by voluntary contributions from Rotary clubs, Rotarians and others. Further gifts, bequests etc. are greatly needed to meet the continuing and expanding needs of the Foundation's programmes.

Polio Plus is a Foundation programme that enacts Rotary's pledge to promote and assist polio immunizations of all children world wide no later than Rotary's 100th anniversary in 2005. The programme provides all the polio vaccine necessary for for up to five consecutive years for any approved immunization programme; and provides, upon invitation, a team of experts to help plan and implement National Immunization Days against polio. A worldwide campaign to fund the programme raised almost US$230 million. The last case of polio in the Western hemisphere occurred in 1992. Rotary has been known to immunize some 90 million children in a single day.

Health, Hunger, and Humanity (3-H) is a programme of the Rotary Foundation which funds large scale, usually one-to-five year humanitarian projects providing benefits of a long-term self-help nature by improving health, alleviating hunger and enhancing human and social development. The 3-H programme also makes arrangements and pays freight cost for donated vaccines, and provides travel and living expenses for expert volunteers in support of humanitarian projects.